Development and characterization of biocompatible isotropic and anisotropic oil-in-water colloidal dispersions as a new delivery system for methyl dihydrojasmonate antitumor drug
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چکیده
License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Ltd, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Ltd. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php International Journal of Nanomedicine 2014:9 867–876 International Journal of Nanomedicine Dovepress
منابع مشابه
Development and characterization of biocompatible isotropic and anisotropic oil-in-water colloidal dispersions as a new delivery system for methyl dihydrojasmonate antitumor drug
Microemulsions (MEs) are colloidal systems that can be used for drug-delivery and drug-targeting purposes. These systems are able to incorporate drugs modifying bioavailability and stability and reducing toxic effects. The jasmonate compounds belong to a group of plant stress hormones, and the jasmonic acid and its methyl ester derivative have been described as having anticancer activity. Howev...
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Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...
متن کاملPreparation and characterization of friendly colloidal Hydroxyapatite based on natural Milk’s casein
Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...
متن کاملOil-in-water biocompatible microemulsion as a carrier for the antitumor drug compound methyl dihydrojasmonate
Methyl dihydrojasmonate (MJ) has been studied because of its application as an antitumor drug compound. However, as MJ is a poorly water-soluble compound, a suitable oil-in-water microemulsion (ME) has been studied in order to provide its solubilization in an aqueous media and to allow its administration by the parenteral route. The ME used in this work was characterized on the pseudo-ternary p...
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The development and design of the biocompatible and biodegradable thermodynamically stable micellar and microemulsion transparent dispersions to reduce the free and unbounded drugs concentration in the blood is a basic challenge in field of drug efficacy and bioavailability of drugs. In the current work, solubilization capacity of the drug (Tocopherol), oil (Ethyl Butyrate), and oil+drug (1:1 m...
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